Endocrine Abstracts

Aim: To evaluate thyroid dysfunction in all patients admitted to hospitals in Aneurin Bevan University Health Board (ABUHB) from October 2019 to September 2021.Method: This report is based on a retrospective observational study of the thyroid tests and case notes of 95 patients admitted to all the hospitals under ABUHB for acute concerns (other than thyroid dysfunction) over 2 years.Results: In-Patient scanned notes and pathology r...

A 54 years old gentleman was admitted to cardiology ward from echocardiography department in view of findings on the scan. He was referred to cardiology clinic on outpatient basis 3 months earlier by his GP for his shortness of breath, ankle swelling and a murmur heard on auscultation by his GP. His transthoracic echocardiography was being conducted prior to attendance at cardiology clinic. The result showed a large global pericardial effusion, max 4.9 cm in size. There was se...

Background: Pituitary haemorrhage or infarction into a pituitary tumour is well reported unlike isolated Pituitary haemorrhage due to traumatic injury of a normal gland.Case report: A previously healthy 44-year-old man presented following two episodes of seizures following a closed head injury. He reported transient extreme thirst, polyuria and headache at the outset, which had resolved by the time of admission. His Glasgow Coma scale was 14/15 and his c...

Background: Pituitary adenomas are broadly classified based on size (microadenomas and macroadenomas) and functionality. While their management has established national and international guidelines based on these two classifications, we aim to evaluate the same in a post-pandemic era, when health care resources are already stretched and have a significant backlog to deal with.Aim: To carry out a retrospective analysis of...

After suffering three spontaneous pneumothoraces, Mr A was due to have definitive treatment in the form of video-assisted thoracoscopy and pleurodesis. Soon after ‘induction of anaesthesia’ he developed severe hypertension; 130/80 →300/220 associated with global high take off and ST elevation on the ECG. Labetol was given i.v. after which the blood pressure became unrecordable and an EMD cardiac arrest ensued. Three cycles of cardiac massage and two boluses of ...

Background: Ischemic stroke is an unusual but important complication of Graves’ Thyrotoxicosis that is induced by the hypoercoaguable state of thyrotoxicosis.We present a 24-year old female patient admitted with a 3-day history of intermittent slurred speech associated with numbness of the right side of her mouth and face preceded by left sided headache.She had a history of uncontrolled Graves’ disease secon...

Background: Ischemic stroke is an unusual but important complication of Graves’ Thyrotoxicosis that is induced by the hypoercoaguable state of thyrotoxicosis.We present a 24-year old female patient admitted with a 3-day history of intermittent slurred speech associated with numbness of the right side of her mouth and face preceded by left sided headache.She had a history of uncontrolled Graves’ disease secon...

Background: Covid 19 infection has previously been reported to be associated with worsening of pre-existing and new onset diabetes mellitus1. However, the association of new onset autoimmune diabetes mellitus after Covid vaccination is not fully recognised in the literature.History: We report the case of a 58-year-old healthy woman who received a Covid 19 vaccination on 14th of Nov 2021. 2 weeks subsequently she was admitted with headache, blurred vision...

Introduction: X-linked adrenoleucodystrophy (XALD) is a progressive disorder affecting adrenal glands, testis, and myelin stability, that normally caused by mutations in ABCD1 (NM_000033) gene There is a failure of β-oxidation of fatty acids within peroxisomes due to reduced activity of very long chain acyl-CoA synthetase and can be diagnosed by the demonstration of elevated very long chain fatty acid.Case report: We report a case of a 32-y...

Objective: Most hypothyroid patients require an optimal dose of 1.6–1.8 μg/body weight (kg) of L-thyroxine to restore a normal TSH. Poor response to treatment can be due to malabsorption, drugs interaction and poor compliance. We conducted a test to determine the likely cause of persistent hypothyroidism in a coeliac patient despite taking supraphysiological doses of L-thyroxine (>1000 μg OD).Case...